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MJFF Biosample and Tissue Resource RFA - Fall 2013

Organisme

The Michael J Fox Foundation has supported several pre-clinical and clinical efforts that have generated valuable biospecimen tissue resources for the research community.

Objecte

The Michael J Fox Foundation are providing an opportunity for researchers to apply to utilize these samples. Resources include animal model tissue from Parkinson’s rodent models, human clinical data and biologic samples (blood, spinal fluid, urine, postmortem tissue) from current and previous clinical studies and trials.
 

Descripció

Pre-Clinical MJFF Resource- Animal Model Tissue: MJFF would like to provide funding to investigators to use existing PD animal model tissue for biochemical and pathological characterization and hypothesis testing. Tissue from the following animals are available: Mice: LRRK2 WT, LRRK2 R1441G, LRRK2 G2019S, Wild-type FVB

Clinical MJFF Resources- DATATOP Biospecimens: This program is launched in collaboration with the Parkinson’s Study Group (PSG) to support the identification and validation of novel biomarkers through use of serum, cerebrospinal fluid, and urine from individuals that participated in a clinical interventional trial. Samples were collected from PD patients at the beginning of the trial and approximately 18 months later. There are no matching control samples that are a part of this cohort.

Postmortem tissue and Samples from the Arizona Parkinson’s Disease Consortium: MJFF is interested in studies that promote the understanding of the clinicopathological correlates of Parkinson’s disease using extensive longitudinal clinical data and postmortem tissue and biological fluids from normal control, PD and related disease subjects. Find out more about available Arizona Parkinson’s Disease Consortium resources.

24-Hour Biofluid Sampling Study: MJFF sponsored an Assay Qualification study that collected blood and cerebrospinal fluid samples in Parkinson’s disease subjects and healthy volunteers over 26 hours for use in biomarker development and assay optimization.
 

FUNDING AVAILABLE: MJFF will commit up to $500,000 to fund proposals submitted in response to this RFP. Applicants may submit a proposal for consideration of one-year, and up to USD $150,000 award.

Please see the program instructions, Administrative Guidelines and our FAQ on MJFF indirect cost policy for details.



ELIGIBILITY REQUIREMENTS Applications may be submitted by:

• U.S. and non-U.S. biotechnology/pharmaceutical companies or other for-profit entities, either publicly or privately held,
• U.S. and non-U.S. entities, public and private non-profit entities, such as universities, colleges, hospitals, laboratories, units of state and local governments, and eligible agencies of the federal government.
• Post-doctoral fellows are eligible to apply as PIs, but must collaborate with an Administrative PI who serves as the director of the laboratory in which the research will be conducted. The Administrative PI will be responsible for assisting in providing all institutional documents required for the project and will be required to sign any award contract. Biographical information is required for both the postdoctoral fellow acting as PI, as well as for the Administrative PI. Responsibility for the planning, direction, and execution of the proposed project will be solely that of the principal investigator.
   

Termini oficial

Informational Conference Call*: March 6, 2013 at 12pm US EDT
Pre-Proposals Due: April 3, 2013
Full Application Invites Sent to Applicants: April 24, 2013
Full Applications Due: June 12, 2013
Anticipated Award Announcement: September 2013
Anticipated Funding: October 2013

*MJFF will hold a 45-minute conference call on the dates and times listed above to clarify and explain the goals of this funding initiative and answer applicant questions. To participate in the call and receive call-in details, please RSVP via email to conferencecalls@michaeljfox.org.
 

Termini IISPV

Termini IISPV: Cal comunicar abans del 5 de març de 2013 que es vol participar a la convocatòria, enviant un e-mail a convocatories@iispv.cat . Termini: 21 de març de 2013

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