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Funding institution



The Prostate Cancer Foundation (www.pcf.org) champions human capital investment to fast-forward solutions to prostate cancer.

The PCF Challenge Awards will fund llarge-scale investigations of metastatic, lethal prostate cancer. Team science awards are composed of at least three (3) investigators from non-profit academic research centers, including one young investigator. High risk, currently unfunded projects are most desired.

Característiques principals
Research proposals in the following topic areas are preferred:

  • Immunotherapy for the treatment of metastatic, lethal prostate cancer.
  • New systemic treatments for metastatic, lethal prostate cancer including those targeting the currently 'undruggable'.
  • First-in-field research on new targets for systemic treatment of metastatic, lethal prostate cancer.
  • Mechanisms of resistance to current and investigational drugs targeting the androgen receptor and androgen axis, immune system and chemotherapy.
  • Correlative research around either clinical trials of novel agents or strategies or standard of care.
  • Developing or validating biomarkers that guide therapy in patients or further our understanding of the mechanisms by which therapies work.
  • Tumor microenvironment signaling related to cancer progression including the immune component.
  • New bioinformatics technologies for analysis of genomic data.

IISPV Deadline

The deadline for application submission is Friday, April 29, 2016, 3:00 p.m. Eastern Daylight Time (EDT)

Documents to be presented

Applications must be submitted online at: https://pcf.smartsimple.com

- Application Form
- Research Proposal: The following sections are required:

  • A scientific abstract
  • Statement of originality (1-page limit)
  • Research Proposal: (10 pages limit)
  • NIH Biosketch
  • Budget
  • Clinical trial protocol and a timeline for activation of the clinical investigation: If applicable.
  • Supplemental Information (Optional): Supplemental information in support of the application such as previous relevant publications, letters of collaboration and letters of support.


$1,000,000 per team


2 years

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